muscle stiffness. (1) Limitations of Use In OSA, PROVIGIL is indicated to treat excessive sleepiness and not as treatment for the underlying obstruction. Modafinil is a medication that has been found to be effective in fighting fatigue and improving alertness in people. On-label use increased by less than 3-fold, whereas off-label use increased more than 15-fold (). Modafinil should not be taken in pregnancy as it could cause harm to the unborn child. 16. The Food and Drugs Administration (FDA) has approved two wakefulness-promoting agents for treating shift work disorder, modafinil Trusted Source U. Modafinil comes as a tablet to take by mouth. This study seeks to describe the utility of the proGAV®2. Fibromyalgia is a syndrome that affects the muscles and soft tissue and its symptoms—chronic muscle pain, fatigue and sleep problems, mimic CFS. Dyspepsia, associated w/, gastric reflux, reflux oesophagitis, heartburn,. 0 (see Fig. )/১০ মি. Keep out of reach of children. 1,2 Progressive and severe curves, if left untreated, may result in compromised pulmonary func-Order Progavi (500 mg+213 mg+325 mg)/10 ml (প্রোগ্যাভি সাসপেনশন) online at the best price in Bangladesh from Medeasy. If you have liver problems, the medication could build up. 8 Idiopathic Hypersomnolence Idiopathic hypersomnolence is a disabling condition (or conditions) characterized by severe EDS in the absence of narcolepsy or other sleep. Unusual thoughts or behavior. AHFS DI Monograph. Alertec: Modafinil belongs to the group of medicines known as central nervous system (CNS) stimulants. For the full list of excipients, see Section 6. Umhau was a senior clinical investigator at the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health (NIH). You should not use Nuvigil if you have ever had a rash or allergic reaction caused by armodafinil or modafinil (Provigil). Subscribe to Drugs. com. Do not keep outdated medicine or medicine no. ozanimod increases toxicity of modafinil by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Using adjustable. Get Coupon. A UK survey found median time from first symptom to diagnosis to be 10. The signal of serious adverse events trended strongest for armodafinil or modafinil (RR 1. Provigil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. It is an eugeroic medication, which means it is wakefulness-promoting agent. Hydrocephalus is divided into two broad categories: communicating and obstructive. Provigil, which comprises the drug modafinil, is a stimulant that originally received FDA approval in 1998. blue® is an unique adjustable gravitational valve for the treatment of adult and pediatric hydrocephalus. Provigil is a medication that promotes wakefulness. Clinical records and imaging of all patients fitted with proGAV®2. Modafinil is a medication that promotes wakefulness. It works by altering neurotransmitters in the brain. In 2000, the manufacturer, Cephalon, conducted a study of modafinil in people with MS to evaluate it as a potential treatment for MS-related fatigue. Effectiveness. An American Academy of Sleep Medicine clinical practice guideline. Provigil is made of two compounds that are mirror images of each other (called an R-isomer and S-isomer). Its generic name is Sodium Alginate + Sodium Bicarbonate + Calcium Carbonate. . 99 for the most common version, by using a GoodRx coupon. Adderall (mixed amphetamine salts) is a psychostimulant drug that was initially approved. The ProGav Miethke shunt is composed of an adjustable ballon-spring valve unit and an integrated over-drainage compensating gravitational device (known as the shunt assistant). trouble in urinating. Pediatric hydrocephalus is one of the most common surgically treatable neurological conditions in children [ 1 ]. The study is designed to assess walking and balance, urinary function, cognitive performance and quality of life before and after shunting and compare the results between the patients with MIETHKE. Products. Provigil (modafinil) indications, usage, warnings, adverse reactions, and more. Sunosi (solriamfetol) is a prescription medicine used for the treatment of excessive sleepiness in adults with narcolepsy or obstructive sleep apnea. . Medication Discount Card LLC does not warrant the accuracy of the information on this website. The response of ICP to valve setting adjustments was classified as ‘expected’ in 54 cases (57%), ‘paradoxical’ in 17 cases (18%) and ‘no effect’ (Δ night ICP < 1 mmHg) in 23 cases (24%). and 8 a. An American Academy of Sleep Medicine clinical practice guideline. Keep from freezing. Keep all medicine out of the reach of children. Three serious adverse events occurred during the study (pulmonary embolism and myocarditis while taking amantadine and a multiple sclerosis exacerbation. MODAVIGIL® (modafinil) is a wakefulness-promoting agent for oral administration. Wakix is a brand-name prescription medication. Narcolepsy with cataplexy is primarily a disorder of excessive daytime sleepiness (EDS) and episodic collapse. Modafinil is a wakefulness-promoting medication that can help you stay awake and alert. However, as discussed above, sodium oxybate (e. Nuvigil is a very similar drug to Provigil. Modafinil (Provigil): This medication is designed to encourage a feeling of wakefulness. The proGAV 2. It belongs to a group of medications called stimulants. Caffeine. Modafinil is a non-amphetamine central nervous system (CNS) stimulant with wakefulness-promoting properties. The right medication and the right dose vary among individuals, so it may take time to find out what's right for you. But it has 90% less salt than the older drug. গ্রা. 19 ₹ 3,899. Includes Sunosi side effects, interactions and indications. Cochlea Medicine & Life Sciences 29%. Modafinil, sold under the brand name Provigil, increases dopamine in the brain, similar to stimulants. Fastest-Acting Modafinil Alternative: Lucy Nicotine. Satisfaction. AccessGUDID - proGAV® (04041906132354)- PROGAV W/CONTROLRESERVOIR. , a serious rash or a serious allergic reaction) that may affect your liver or blood cells. indigestion. Provigil is a prescribed medication used for the treatment of ADHD. It is sparingly to slightly soluble in ethanol and acetone. Progavi is indicated in Gastric reflux, Heartburn, Flatulence associated with gastric reflux, Heartburn of pregnancy, All cases of epigastric and retrosternal distress where the. heartburn. 5 years. This medicine is available only with your doctor's prescription. ; Renal. 04 mmHg ml-1 min-1). 200 mg orally once a day in the morning. You can go with a methylphenidate to dexmethylphenidate substitution (or vice versa). This medication contains modafinil. But as always, talk to your doctor first before making any. Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Provigil can cost more than $950 out-of-pocket, but with a coupon from SingleCare, you could get a 30-day supply of the generic for less than $60. Overall rating 5. g. Major: Highly clinically. PROVIGIL is used to treat excessive sleepiness, but not the obstruction or medical condition that is causing OSA. Modafin (modafinil) is a wakefulness-promoting agent for oral administration. This study seeks to describe the utility of the proGAV®2. Modafinil is used to help people who have narcolepsy, obstructive sleep apnea/hypopnea syndrome (OSAHS), or shift work sleep disorder (SWSD) to stay awake during the day. Armodafinil is used for treating problems related. Sunosi. +৩২৫ মি. Modafinil tablets are a prescription medicine used to improve wakefulness in adults who are very sleepy due to one of the following diagnosed sleep disorders: narcolepsy; obstructive sleep apnea (OSA). Modafinil does not cure these conditions and will only work as long as you continue to take it. They concluded that the drug. See moreGeneric Name: modafinil Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep ( obstructive. )/১০ মি. Modafinil, available under the brand name Provigil, is a central nervous system stimulant drug. If a psychotropic medication is discontinued preoperatively, a plan for exactly when this can be restarted postoperatively should be decided, with special consideration if oral medications are not an option. +২১৩ মি. 7. Address reprint requests to Dr. Progavi Syrup-200 ml Modafinil demonstrated a clear beneficial effect on excessive daytime sleepiness in patients with PD (mean difference in scores on the Epworth Sleepiness Scale between modafinil and placebo PD groups=–2. All information on this site is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist. Alleviates the painful conditions resulting from gastric acid & bile reflux into oesophagus. Modafinil is well distributed in body tissue with an apparent volume of distribution (~0. Provigil is a medication prescribed to promote wakefulness in those who find it difficult to stay awake. It decreases excessive sleepiness caused by narcolepsy and other sleep disorders, obstructive sleep apnea. Possible side effects of modafinil are headaches, dry mouth, nausea, diarrhea, loss of appetite and weight loss. The proGAV is a position-dependent valve. Introduction. Unlike other adjustable valves, the proGAV® cannot be accidentally re-adjusted by external magnetic fi eld such as a 3T MR scanner. Provigil is a brand-name prescription medication manufactured by Teva Pharmaceuticals. We hypothesized that 200 mg of modafinil daily for 6 weeks would result in reduced symptoms of fatigue compared with placebo. Is Provigil a stimulant? Yes, Provigil drug class is stimulant, and Modafinil schedule is Schedule IV controlled substance according to information from the United States Drug Enforcement Agency (DEA). Three proGAV. Reviews and ratings for Modafinil. Patient has tried generic modafinil or generic armodafinil; AND ii. Modafinil (Provigil) is a prescription medication used to improve wakefulness in people who have extreme sleepiness due to narcolepsy, obstructive sleep apnea, or shift work disorder. Modafin tablet contains 100 mg of modafinil. A mechanical 'brake' is intended to prevent changes to the valve's performance level in a strong magnetic field. This means that the opening pressure varies depending on the body position of the patient. It is essential to discuss with a clinical care expert before adjusting daily dose and treatment. Provigil mediciation is intended to. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. 0 valves and Miethke fixed-pressure valves between 2014 and 2019 at our tertiary centre were analysed. Figure 1. Modafinil has been shown to significantly increase dopamine in the brain by blocking dopamine transporters; however, has a lower affinity for dopamine receptors compared to amphetamines (Volkow 2009). It is sometimes used off-label to treat symptoms of ADHD in adults 18 years of age and older. Some people need treatment with methylphenidate (Ritalin, Concerta, others) or amphetamines (Adderall XR 10,. What is PROVIGIL? PROVIGIL is a prescription medicine used to improve wakefulness in adults who are very sleepy due to one of the following diagnosed sleep disorders: narcolepsy; obstructive sleep apnea (OSA). This stimulation likely mediates the drug's ability to promote wakefulness and counteract cellular damage (1). Contains sugars as lactose. গ্রা. People who take modafinil for an extended amount of time may develop drug dependence. Pre-clinical studies of modafinil suggest a complex profile of. g. Nuvigil Alternatives Compared. Expand current row for information about calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate. Side effects are uncommon but may include headache, nausea or anxiety. If you are taking modafinil to treat shift work sleep disorder, you will probably take it 1 hour before the beginning of your work shift. Differential pressure valves are a popular treatment modality, with evidence suggesting that incorporation of gravitational units helps minimise over-drainage. Download Practo app. গ্রা. Achieving decompression without CSF over-drainage remains a challenge in hydrocephalus. +৩২৫ মি. You should not use Nuvigil if you are allergic to armodafinil or modafinil (Provigil). 92% of reviewers reported a positive experience, while 0% reported a. Auvelity is an antidepressant medicine used to treat Major Depressive Disorder (MDD) which is a specific type of depression. Modafinil can also be abused for its effects. cerivastatin Medicine & Life Sciences 28%. Within 3 days of taking Provigil, I was the happiest, most productive I had been in a year. Common side effects of Provigil include headache, upper respiratory tract infection, nausea, nervousness, anxiety, and insomnia. 223. Symmetrel (amantadine) Provigil (modafinil) Prozac (fluoxetine) Ritalin (Methylphenidate) Next Steps. Modafinil is a medication used to treat narcolepsy and other sleep disorders. DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service Food and Drug Administration 10903 New Hampshire Avenue Document Control Center - WO66-G609 Silver Spring, MD 20993-0002 Provigil is a prescription medication that is typically covered by commercial insurance. Take a lukewarm shower or bath 60-90 minutes before bed. It is not known how modafinil works to keep you awake. There are Modafinil over-the-counter and natural alternatives that are deemed effective, and these are listed below. Modafin (modafinil) is a wakefulness-promoting agent for oral administration. 00 GET 25 % off. 800. It works by exciting your nervous system to release chemicals that make you feel more energetic. 0 programmable valve in a paediatric population. Despite a quality of life impact similar to Parkinson's disease (PD) 1 and significant individual and societal costs 2 it is often overlooked. Provigil binds to the same receptor sites in the brain as cocaine and crystal meth, only to a much milder extent. Modafinil is believed to increase dopamine levels, which helps improve wakefulness. 0 Valve is a position-dependent valve, meaning the opening pressure changes gradually corresponding to the patient's body position. shortness of breath. The proGAV 2. Giacino at the Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, 125 Nashua St. Department of Neurosurgery, School of Medicine, Second Affiliated Hospital, Zhejiang University, Hangzhou, China; Objective: To evaluate the outcomes and prognostic factors of ventriculoperitoneal shunts (VP-shunts) in patients with idiopathic normal-pressure hydrocephalus (iNPH) at 6 months and 2 years after surgery. In 2003, Cephalon (a parent company – Teva Pharmaceuticals) submitted to the FDA a supplemental application that would give medical specialists a free hand to prescribe Provigil medicine for lesser sleep disorders, such as shift-work drowsiness. You need to not breast-feed while using this medication. )/১০ মি. with medication, support, and. It’s a prescription drug used to relieve excessive sleepiness in adults. Modafinil /armodafinil. This medication is designed to be longer-acting than other amphetamine formulations. 0. Molecular and biologic characteristics of modafinil. This means that the opening pressure varies depending on the body position of the patient. Hide glossary Glossary. proGAV® 2. Modafinil is the world’s first safe “smart drug”, researchers at Harvard and Oxford universities have said, after performing a comprehensive review of the drug. Off-label it has been used to help people with Parkinson's Disease, ADHD, chronic fatigue. Modafinil is contraindicated in patients with moderate to severe hypertension and may reduce the efficacy of low dose oral contraceptives via enzymatic. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Modafinil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. We offer the most competitive prices and free pills with every order. Differential pressure valves are a popular treatment modality, with evidence suggesting that incorporation of gravitational units helps minimise over-drainage. Seek immediate medical help on the occurrence of any such side effect as it can endanger life. Chemical structure of modafinil is shown in Figure 1. Last reviewed on January 22, 2021. Provigil Contraindications. Its generic name is Sodium Alginate + Sodium Bicarbonate + Calcium Carbonate. To make sure Nuvigil is safe for you, tell your doctor if you have ever had: liver or kidney disease; heart disease or a heart muscle or valve disorder such as mitral valve prolapse; Nuvigil and Provigil have different chemical structures. It has also been used to treat sleep apnea, narcolepsy, and other sleep disorders. Tell your doctor about any side effects. In case of overdose, get medical help or contact a Poison Control Center immediately; Contraindications. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. 4 more events per 1,000. It's considered a controlled substance since this medication has a potential to cause misuse. 17 PATIENT COUNSELING INFORMATION. 75, which is 97% off the average retail price of $719. It is an effective medication approved for promoting wakefulness in individuals with sleep disorders. 9 L/kg) larger than the volume of total body water (0. Progavi Suspension (500 mg+213 mg+325 mg)/10 ml (প্রোগ্যাভি (৫০০ মি. Pitolisant also may be helpful for cataplexy. From the beginning, we have worked with patients, doctors, distribution partners and critics to confidently deliver a superior product. PROVIGIL 100 MG. লি. Modafinil: Side Effects, Drug Interactions, and Mechanisms of Action. Expand to see all locations within your area. A patient with theModafinil may also induce its own metabolism. calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate. LABORATORY INVESTIGATION J Neurosurg Pediatr 26:667–670, 2020 E arly-onsEt scoliosis is a condition defined by spinal curvature greater than 10 ° beginning before the age of 10 years. 10. A greater proportion of modafinil-treated patients required new or increased use of antihypertensive medication compared with those receiving placebo in a retrospective analysis (2. Two clinical trials compared different doses (200 mg and 400 mg) of modafinil with placebo. The difference in structure between Nuvigil and Provigil affects how long each medication lasts in the body. (A drug class describes a group of. SUNOSI does not treat the underlying cause of OSA and SUNOSI does not take the place of any device prescribed for OSA, such as a continuous positive. Modafinil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep. The proGAV 2. গ্রা. Provigil is prescribed to increase wakefulness in patients with excessive sleepiness related to narcolepsy, shiftwork sleep disorder, and obstructive sleep apnea/hypopnea syndrome. Top choices include Adderall (amphetamine) and Ritalin (methylphenidate) — treatments for attention-deficit hyperactivity disorder (ADHD) — and modafinil, which is a medication for sleep. A variation of the medication, marketed as Nuvigil and composed of armodafinil, was approved by the FDA in 2007. Its generic name is Sodium Alginate + Sodium Bicarbonate + Calcium Carbonate. 78. Modafinil may also be used for purposes not listed in this medication guide. Users find that Modafinil keeps them wide awake, ultra-motivated and hyper-focused for 6-8 hours at a time, all without really making them feel like they’re “on” medication. as low as. 2 out of 10 from a total of 13 reviews for the treatment of Shift Work Sleep Disorder. 0: January 2015–December 2016) with subsequent 30-month follow-up period, respectively. g. However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL (modafinil) required new or increased use of antihypertensive medications (2. The exact mechanism of action is unclear. Nuvigil is used in adults to treat: narcolepsy. 2273 100 Years of Cleveland Clinic This medicine is available only with your doctor's prescription. Background Idiopathic normal-pressure hydrocephalus (iNPH) is a distinct form of dementia, characterized by gait ataxia, cognitive impairment and urinary incontinence. 1. This study aimed to assess the efficacy of modafinil, a wakefulness-promoting agent in alleviating post-stroke fatigue ≥3 months after stroke. Stimulant medication, such as modafinil (Provigil, Alertec), might be prescribed to help you stay awake during the day. ; Hepatic Impairment: No dose modification necessary. Provigil (modafinil) is a medication that promotes wakefulness. This medication may not be approved by the FDA for the treatment of this condition. Treatment. Provigil and Nuvigil. Every effort has. Some people need treatment with methylphenidate (Ritalin, Concerta, others) or amphetamines (Adderall XR 10, Dexedrine, others). Provigil Alternatives Compared. Modafinil has been linked to irregular heartbeats (arrhythmias) and increases in blood pressure, so you'll need to be regularly monitored during treatment to check for these problems. Modafinil is a prescription medication classified as a eugeroic, a type of wakefulness-promoting agent. Under the brand name Provigil, modafinil is a central nervous system stimulant that treats sleep disorders by improving wakefulness. 0 programmable valve in a paediatric population. Your data will only be used for strictly appropriated processing and for answering your request. গ্রা. AccessGUDID - proGAV 2. Also, the brain needs lots of rest for its normal functions, and because of the lack of adequate rest, Provigil induces a. Since the efficacy of modafinil is consistently described and there is much experience with this substance, it is reasonable to start with modafinil as a first choice treatment. , caused by hydrocephalus). Prescribed for Narcolepsy, Shift Work Sleep Disorder, Obstructive Sleep Apnea/Hypopnea Syndrome. Although. We found the Certas TM valve valuable in the treatment of hydrocephalus, usability of the TMS was high because it is small and portable, but in some cases we experienced adjustment problems with the first procedures performed by a surgeon, indicating that there is a learning curve. At serum concentrations obtained at steady state after doses of 200 mg/day, modafinil. Purpose Achieving decompression without CSF over-drainage remains a challenge in hydrocephalus. Generic Name: modafinil Modafinil reduces extreme sleepiness due to narcolepsy and other sleep disorders, such as periods of stopped breathing during sleep ( obstructive sleep apnea ). Call Today! (844) 616-3400. The wake-promoting agent modafinil is approved for the treatment of excessive sleepiness associated with obstructive sleep apnea (OSA), shift work disorder (SWD), and narcolepsy. Progavi Syrup-200 mlHow Progavi Oral Suspension (500 mg+213 mg+325 mg)/10 ml works. The first 2 days I was still really sleepy, and the 3rd day, a little hyper, but after that. Pitolisant also may be helpful for cataplexy. Modvigil is a very effective generic Modafinil medication that is used by students, CEOs, and professionals to stay ahead of the competition. Provigil has an average rating of 9. This medication does not cure these sleep disorders and may not get rid of all your sleepiness. Modafinil has been shown in clinical investigations to mildly impede dopamine and norepinephrine transit, thereby boosting norepinephrine and dopamine neurotransmission. 6 L/kg). Modafinil has also become increasingly used as a recreational drug. There are currently no medications specifically approved for the treatment of sleep disruption, which many people with narcolepsy and a subgroup of PWIH experience. This product is available in the following dosage forms: Tablet; Before Using. Second, these agents are controlled substances due to their risk for potential misuse. 0 Valve provides the reliability of existing MIETHKE Gravitational Valves, with new features to ensure simplicity for the surgeon, along with comfort and protection for the patient. Nuvigil is used in adults to treat: narcolepsy. Modafinil, sold under the brand name Provigil among others, is a central nervous system stimulant medication used to treat sleepiness due to narcolepsy, shift work sleep disorder, and obstructive sleep apnea. Excipients with known effect. Modafinil is a racemic compound and the chemical name is 2-[(diphenylmethyl)sulfinyl] acetamide. Positron emission tomography (PET) has been widely used in paediatric oncology. unusual tiredness or weakness. Although the VPS extends survival. There was a significant. The generic version of Provigil is modafinil. FORM FDA 3881 (8/14) Page 1 of 1 PSC Publishing Services (301) 443-6740 EF DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Indications for UseProvigil is a prescription medication that is typically covered by commercial insurance. 7 reviews. Buy Progermina Suspension Online. This one may be shocking. Sunosi and modafinil are similar medications. Xyrem isn’t a stimulant, so it works in a different way. Before taking this medicine. 7%). Both doses of modafinil improved the patients' symptoms, but not all of the changes were significantly greater. rapidly changing moods. Provigil has helped quite a bit but does have some cons. Wakix is a histamine-3 blocker, and it acts. This guideline, in conjunction with the accompanying. Modafinil is a prescription medication known as a "eugeroic" which are wakefulness promoting drugs that stimulate the central nervous system by affecting the circadian rhythm part of the brain. Ask your doctor or pharmacist if you have any questions. Provigil belongs to a class of drugs called. (An active ingredient is what makes a drug work. ADD TO CART. This means that it can be optimally adapted to the. The postoperative course of 55 proGAV ® and 45 programmable Codman Hakim ® patients was analyzed. When prescribed for cocaine or crystal meth addiction, Modafinil acts as a medication-assisted therapy (MAT). ) is a product of Beximco Pharmaceuticals Ltd. Learn more about its features, benefits and clinical outcomes in this brochure from Aesculap, a leading provider of surgical and medical solutions. Keep all medicine out of the reach of children. An implantable device intended to function as part of a lumboperitoneal, ventriculoperitoneal or ventriculoatrial shunt to regulate the pressure and flow level of cerebrospinal fluid (CSF) from the lumbar spine or brain to the. References. Modafinil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder. 0® (04041906136550)- PROGAV 2. In case of cancellation your data will be deleted immediately. The benefits of. Different individuals may respond to medication in different ways. per day), and may translate into an improved side-effect profile. Under the brand name Provigil, modafinil is a central nervous system stimulant that treats sleep disorders by improving wakefulness. 9). Further, the recently reported cognitive-enhancing actions of (±)-modafinil, especially in methamphetamine abusers ( 12 ) suggest that additional. 0 like its predecessor, is a. It’s most often used to treat excessive sleepiness caused by narcolepsy, obstructive sleep apnea, and shift work. sleep problems (insomnia). Modafinil is not an amphetamine, but it is a therapy approved for people who do shift-work. It is used to help people with a condition called narcolepsy, which causes daytime excessive sleepiness, by preventing drowsiness and keeping these people from falling asleep. Provigil has been the only medication out of the tons I have been previously prescribed that finally worked in helping me stay awake. This kind of medication has only been used to treat sleeping concerns such as sleep apnea, obstructive sleep apnea, and circadian rhythm disorders such as shift work. Numerous clinical studies have shown that gravitational valves are able to reduce secondary complications of VPS treatment. Tell your doctor if you have serious side effects of Nuvigil including: fast/pounding/irregular heartbeat, or.